Genistein appears to prevent early postmenopausal bone loss as effectively as hormone replacement therapy

被引：50

作者：

Cotter, A ^{[1
]}

Cashman, KD

机构：

[1] Natl Univ Ireland Univ Coll Cork, Dept Nutr & Food Sci, Cork, Ireland

[2] Natl Univ Ireland Univ Coll Cork, Dept Med, Cork, Ireland

来源：

NUTRITION REVIEWS | 2003年 / 61卷 / 10期

关键词：

genistein; phytoestrogens; postmenopausal bone loss; HRT;

D O I：

10.1301/nr.2003.oct.346-351

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Recent data from a randomized, double-blind, placebo-controlled, yearlong clinical trial suggest that supplementation with the dietary phytoestrogen genistein (54 mg/day) may be as effective as hormone replacement therapy in attenuating menopause-related bone loss without causing the associated side effects. These findings may have implications for the development of diet-based strategies aimed at osteoporosis prevention.

引用

页码：346 / 351

页数：6

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