The occurrence of 7-epi-pectenotoxin-2 seco acid in the coastal waters of the central Adriatic (Kastela Bay)

被引：24

作者：

Pavela-Vrancic, M

Mestrovic, V

Marasovic, I

Gillman, M

Furey, A

James, KK

机构：

[1] Univ Split, Fac Nat Sci Math & Educ, Dept Chem, Split 21000, Croatia

[2] Inst Oceanog & Fisheries, Split 21000, Croatia

[3] Inst Technol, Dept Chem, Cork, Ireland

来源：

TOXICON | 2001年 / 39卷 / 06期

关键词：

Adriatic Sea; phytoplankton toxins; Diarrhetic Shellfish Poisoning; 7-epi-pectenotoxin-2 seco acid;

D O I：

10.1016/S0041-0101(00)00203-8

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Okadaic acid (OA) and 7-epi-pectenotoxin-2 seco acid (7-epi-PTX-2SA*) were identified as the toxic determinants in mussels from the central Adriatic Sea. The nature of the pectenotoxin-2 derivative was confirmed by chromatographic comparison with toxins present in algae extracts of Dinophysis acuta from Ireland, and by mass spectrometric analysis. The origin of shelfish toxicity has been associated with the occurrence of the Dinophysis species. This is the first report on the incidence of 7-epi-PTX-2SA in the Adriatic region. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：771 / 779

页数：9

共 27 条

[1]

[Anonymous], MARINE COASTAL EUTRO

[2]

Baric A., 1992, CHEM ECOL, V6, P51, DOI [10.1080/02757549208035262, DOI 10.1080/02757549208035262]

[3]

BONI L, 1993, DEV MAR BIO, V3, P475

[4] Structures of new pectenotoxin analogs, pectenotoxin-2 seco acid and 7-epi-pectenotoxin-2 seco acid, isolated from a dinoflagellate and greenshell mussels [J].