Interferon treatment on glomerulonephritis associated with hepatitis C virus

被引：12

作者：

Matsumoto, S

Nakajima, S

Nakamura, K

Etani, Y

Hirai, H

Shimizu, N

Yokoyama, H

Kobayashi, Y

Tajiri, H

Shima, M

Okada, S

机构：

[1] Osaka Univ, Grad Sch Med Sci, Dept Pediat, Osaka 5650871, Japan

[2] Kanazawa Univ, Sch Med, Div Blood Purificat, Kanazawa, Ishikawa 920, Japan

[3] Osaka Kosei Nenkin Hosp, Dept Pathol, Osaka, Japan

来源：

PEDIATRIC NEPHROLOGY | 2000年 / 15卷 / 3-4期

关键词：

hepatitis C virus; mesangial proliferative glomerulonephritis interferon-alpha;

D O I：

10.1007/s004670000467

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We report on a 10-year-old girl with glomerulonephritis associated with hepatitis C virus infection, who was treated with interferon-alpha. On the first renal biopsy at 8 years of age, mild mesangial hypercellularity in a segmental to semiglobal pattern was present in all glomeruli. After 6 months interferon-alpha therapy, proteinuria diminished completely. However, mesangial proliferation was advanced on the second biopsy at 10 years of age. We concluded that the interferon-alpha was effective in the treatment of proteinuria despite the lack of pathological improvement.

引用

收藏

页码：271 / 273

页数：3

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