hmChIP: a database and web server for exploring publicly available human and mouse ChIP-seq and ChIP-chip data

被引：35

作者：

Chen, Li ^{[1
]}

Wu, George ^{[1
]}

Ji, Hongkai ^{[1
]}

机构：

[1] Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Dept Biostat, Baltimore, MD 21205 USA

来源：

BIOINFORMATICS | 2011年 / 27卷 / 10期

关键词：

EMBRYONIC STEM-CELLS; GENE-EXPRESSION; GENOME BROWSER; UCSC;

D O I：

10.1093/bioinformatics/btr156

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

hmChIP is a database of genome-wide chromatin immunoprecipitation (ChIP) data in human and mouse. Currently, the database contains 2016 samples from 492 ChIP-seq and ChIP-chip experiments, representing a total of 170 proteins and 11 069 914 protein-DNA interactions. A web server provides interface for database query. Protein-DNA binding intensities can be retrieved from individual samples for user-provided genomic regions. The retrieved intensities can be used to cluster samples and genomic regions to facilitate exploration of combinatorial patterns, cell-type dependencies, and cross-sample variability of protein-DNA interactions.

引用

页码：1447 / 1448

页数：2

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