Natural products to drugs: natural product-derived compounds in clinical trials

被引：625

作者：

Butler, Mark S. ^{[1
,2
]}

机构：

[1] MerLion Pharmaceut, Singapore 117528, Singapore

[2] Natl Univ Singapore, Dept Chem, Singapore 117543, Singapore

来源：

NATURAL PRODUCT REPORTS | 2008年 / 25卷 / 03期

关键词：

D O I：

10.1039/b514294f

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Natural product and natural product-derived compounds that are being evaluated in clinical trials or are in registration (as at 31st December 2007) have been reviewed, as well as natural product-derived compounds for which clinical trials have been halted or discontinued since 2005. Also discussed are natural product-derived drugs launched since 2005, new natural product templates and late-stage development candidates.

引用

页码：475 / 516

页数：42

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