Adult stem cells: Simply a tool for regenerative medicine, or an additional piece in the puzzle of human aging?

被引:17
作者
Tollervey, James R. [1 ]
Lunyak, Victoria V. [1 ]
机构
[1] Buck Inst Res Aging, Novato, CA USA
关键词
ADIPOSE-TISSUE; IFATS COLLECTION; STROMAL CELLS; CELLULAR SENESCENCE; GENE-EXPRESSION; FAT TISSUE; TRANSPLANTATION; MECHANISMS; CAPACITY; THERAPY;
D O I
10.4161/cc.10.24.18832
中图分类号
Q2 [细胞生物学];
学科分类号
071013 [干细胞生物学];
摘要
Adult stem cells have taken center stage in current research related to regenerative medicine and pharmacogenomic studies seeking new therapeutic interventions. As we learn more about these cells, it is becoming apparent that the next big leap in our understanding of adult stem cell biology and adult stem cell aging will depend on the integration of approaches from various disciplines. Major advances and technological breakthroughs at the crossroad of fields such as biomaterials, genomics, epigenomics, and proteomics will enable the design of better tools to model human diseases, and warrant safe usage of adult stem cells in the clinic. © 2011 Landes Bioscience.
引用
收藏
页码:4173 / 4176
页数:4
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