The recognition of facial affect in autistic and schizophrenic subjects and their first-degree relatives

被引:177
作者
Bölte, S [1 ]
Poustka, F [1 ]
机构
[1] Goethe Univ Frankfurt, Klin Psychiat & Psychotherapie Kindes & Jungendal, Dept Child & Adoelscent Psychiat, D-60528 Frankfurt, Germany
关键词
D O I
10.1017/S0033291703007438
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Background. Autism and schizophrenia are considered to be substantially influenced by genetic factors. The endophenotype of both disorders probably also includes deficits in affect perception. The objective of this study was to examine the capacity to detect facially expressed emotion in autistic and schizophrenic subjects, their parents and siblings. Method. Thirty-five subjects with autism and 102 of their relatives, 21 schizophrenic subjects and 46 relatives from simplex (one child affected) and multiplex (more than one child affected) families, as well as an unaffected control sample consisting of 22 probands completed a 50-item computer-based test to assess the ability to recognize basic emotions. Results. The autistic subjects showed a poorer performance on the facial recognition test than did the schizophrenic and the unaffected individuals. In addition, there was a tendency for subjects from multiplex families with autistic loading to score lower on the test than individuals from simplex families with autistic loading. Schizophrenic subjects and their relatives as well as siblings and parents of autistic subjects did not differ from the sample of unaffected subjects in their ability to judge facial affect. Conclusions. Findings corroborate the assumption that emotion detection deficits are part of the endophenotype of autism. In families with autistic children, the extent of facial recognition deficits probably indexes an elevation in familial burden. It seems unlikely that problems in emotion perception form a consistent part of the endophenotype of schizophrenia or the broader phenotype in relatives of patients with psychosis or autism.
引用
收藏
页码:907 / 915
页数:9
相关论文
共 61 条
  • [1] Abnormal processing of social information from faces in autism
    Adolphs, R
    Sears, L
    Piven, J
    [J]. JOURNAL OF COGNITIVE NEUROSCIENCE, 2001, 13 (02) : 232 - 240
  • [2] Autism: The phenotype in relatives
    Bailey, A
    Palferman, S
    Heavey, L
    Le Couteur, A
    [J]. JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 1998, 28 (05) : 369 - 392
  • [3] Parents of children with Asperger Syndrome: What is the cognitive phenotype?
    BaronCohen, S
    Hammer, J
    [J]. JOURNAL OF COGNITIVE NEUROSCIENCE, 1997, 9 (04) : 548 - 554
  • [4] A review of subtyping in autism and proposed dimensional classification model
    Beglinger, LJ
    Smith, TH
    [J]. JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 2001, 31 (04) : 411 - 422
  • [5] Bolte G, 2001, EPIDEMIOLOGY, V12, pS47
  • [6] The cognitive structure of higher functioning autism and schizophrenia:: A comparative study
    Bölte, S
    Rudolf, L
    Poustka, F
    [J]. COMPREHENSIVE PSYCHIATRY, 2002, 43 (04) : 325 - 330
  • [7] The factor structure of the Autism Diagnostic Interview-Revised (ADI-R):: A study on the dimensional versus the categorical classification of autistic disorders
    Bölte, S
    Poustka, F
    [J]. ZEITSCHRIFT FUR KINDER-UND JUGENDPSYCHIATRIE UND PSYCHOTHERAPIE, 2001, 29 (03): : 221 - 229
  • [8] A CASE - CONTROL FAMILY HISTORY STUDY OF AUTISM
    BOLTON, P
    MACDONALD, H
    PICKLES, A
    RIOS, P
    GOODE, S
    CROWSON, M
    BAILEY, A
    RUTTER, M
    [J]. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES, 1994, 35 (05): : 877 - 900
  • [9] THE DEVELOPMENT OF EMOTIONAL CONCEPTS IN AUTISM
    BORMANNKISCHKEL, C
    VILSMEIER, M
    BAUDE, B
    [J]. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES, 1995, 36 (07): : 1243 - 1259
  • [10] Exploring the cognitive phenotype of autism:: Weak "central coherence" in parents and siblings of children with autism:: II.: Real-life skills and
    Briskman, J
    Happé, F
    Frith, U
    [J]. JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY, 2001, 42 (03) : 309 - 316