Turning it on and off: M-phase promoting factor during meiotic maturation and fertilization

被引：159

作者：

Jones, KT ^{[1
]}

机构：

[1] Med Sch Newcastle Upon Tyne, Sch Cell & Mol Biosci, Cell & Dev Physiol Res Grp, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England

来源：

MOLECULAR HUMAN REPRODUCTION | 2004年 / 10卷 / 01期

关键词：

cell cycle; cyclin B; CDK1; mammals; oocyte;

D O I：

10.1093/molehr/gah009

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Maturation (M-phase) promoting factor (MPF) plays a pivotal role in oocytes during their maturation. This review concentrates on its function at three important time-points. First, its activation during meiotic progression from prophase I arrest at germinal vesicle breakdown. Second, its role during the transition from meiosis I to meiosis II, a defining feature of meiosis involving segregation of homologous chromosomes. Third, maintenance of its activity at metaphase II arrest and the necessity for its destruction during oocyte activation. An understanding of how oocytes switch it on and turn it off underpins much of the basic cell biology of oocyte maturation.

引用

收藏

页码：1 / 5

页数：5

相关论文

共 66 条

[1] Activation of the proteasome during Xenopus egg activation implies a link between proteasome activation and intracellular calcium release [J].

Aizawa, H ;

Kawahara, H ;

Tanaka, K ;

Yokosawa, H .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1996, 218 (01) :224-228

[2] Meiotic abnormalities of c-mos knockout mouse oocytes: Activation after first meiosis or entrance into third meiotic metaphase [J].

Araki, K ;

Naito, K ;

Haraguchi, S ;

Suzuki, R ;

Yokoyama, M ;

Inoue, M ;

Aizawa, S ;

Toyoda, Y ;

Sato, E .

BIOLOGY OF REPRODUCTION, 1996, 55 (06) :1315-1324

[3] Fission yeast Bub1 is essential in setting up the meiotic pattern of chromosome segregation [J].

Bernard, P ;

Maure, JF ;

Javerzat, JP .

NATURE CELL BIOLOGY, 2001, 3 (05) :522-526

[4] Kinetochore fibers are not involved in the formation of the first meiotic spindle in mouse oocytes, but control the exit from the first meiotic M phase [J].

Brunet, S ;

Maria, AS ;

Guillaud, P ;

Dujardin, D ;

Kubiak, JZ ;

Maro, B .

JOURNAL OF CELL BIOLOGY, 1999, 146 (01) :1-11

[5] Remodelling the walls of the nucleus [J].

Burke, B ;

Ellenberg, J .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2002, 3 (07) :487-497

[6] Activation of the proteasomes of sand dollar eggs at fertilization depends on the intracellular pH rise [J].

Chiba, K ;

Alderton, JM ;

Hoshi, M ;

Steinhardt, RA .

DEVELOPMENTAL BIOLOGY, 1999, 209 (01) :52-59

[7] THE INDUCTION OF REVERSIBLE AND IRREVERSIBLE CHROMOSOME DECONDENSATION BY PROTEIN-SYNTHESIS INHIBITION DURING MEIOTIC MATURATION OF MOUSE OOCYTES [J].

CLARKE, HJ ;

MASUI, Y .

DEVELOPMENTAL BIOLOGY, 1983, 97 (02) :291-301

[8] DISRUPTION OF C-MOS CAUSES PARTHENOGENETIC DEVELOPMENT OF UNFERTILIZED MOUSE EGGS [J].

COLLEDGE, WH ;

CARLTON, MBL ;

UDY, GB ;

EVANS, MJ .

NATURE, 1994, 370 (6484) :65-68

[9] Role of cyclic nucleotide phosphodiesterases in resumption of meiosis [J].

Conti, M ;

Andersen, CB ;

Richard, FJ ;

Shitsukawa, K ;

Tsafriri, A .

MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1998, 145 (1-2) :9-14

[10] Acquisition of meiotic competence in growing mouse oocytes is controlled at both translational and posttranslational levels [J].

deVantery, C ;

Stutz, A ;

Vassalli, JD ;

SchorderetSlatkine, S .

DEVELOPMENTAL BIOLOGY, 1997, 187 (01) :43-54

← 1 2 3 4 5 6 7 →