Antitumor agents. 193. A high yield preparation of 2-fluoropodophyllotoxin

被引：21

作者：

VanVliet, DS ^{[1
]}

Lee, KH ^{[1
]}

机构：

[1] Univ N Carolina, Sch Pharm, Div Med Chem & Nat Prod, Nat Prod Lab, Chapel Hill, NC 27599 USA

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 12期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(99)00220-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The high yield synthesis of 2-fluoropodophyllotoxin is presented. This preparation represents the first example of a 100% diastereospecific electrophilic fluorination, (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：2259 / 2262

页数：4

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