Invasive infections due to Clavispora lusitaniae

被引：15

作者：

Krcmery, V

Mateicka, F

Grausova, S

Kunova, A

Hanzen, J

机构：

[1] Univ Trnava, Sch Publ Hlth, Trnava 91743, Slovakia

[2] Univ Trnava, Postgrad Med Sch, Trnava 91743, Slovakia

[3] Natl Canc Inst, Dept Microbiol, Bratislava, Slovakia

[4] Natl Canc Inst, Dept Oncol, Bratislava, Slovakia

[5] St Elisabeths Canc Inst, Bratislava, Slovakia

[6] HP Microbiol Ctr, Dept Microbiol, Bratislava 84101, Slovakia

来源：

FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY | 1999年 / 23卷 / 01期

关键词：

D O I：

10.1111/j.1574-695X.1999.tb01719.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Three cases of Clavispora lusitaniae invasive fungal infections are reported. All three infections appeared in cancer patients presented with fungaemia, one additionally with meningitis. Two of them were breakthrough - they developed during therapy with conventional amphotericin B with a dose of 0.5 mg kg(-1) day(-1). All three were cured: two with intravenous fluconazol and one with an increasing dose (1 mg kg(-1) day(-1)) of amphotericin B. Ln one of two breakthrough cases the sensitivity of the strain to antifungals was tested against antifungal agents and showed in vitro resistance to amphotericin B (MIC 2 eta g ml(-1)). (C) 1999 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.

引用

页码：75 / 78

页数：4

共 19 条

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