CD4 cell count-guided treatment interruption: Be smart and wait for more evidence

被引:5
作者
Arduino, R [1 ]
机构
[1] Univ Texas, Hlth Sci Ctr, Dept Internal Med, Div Infect Dis, Houston, TX 77030 USA
关键词
D O I
10.1086/427885
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
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页码:735 / 737
页数:3
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共 15 条
[1]   Long-cycle structured intermittent versus continuous highly active antiretroviral therapy for the treatment of chronic infection with human immunodeficiency virus: Effects on drug toxicity and on immunologic and virologic parameters [J].
Dybul, M ;
Nies-Kraske, E ;
Daucher, M ;
Hertogs, K ;
Hallahan, CW ;
Csako, G ;
Yoder, C ;
Ehler, L ;
Sklar, PA ;
Belson, M ;
Hidalgo, B ;
Metcalf, JA ;
Davey, RT ;
Kress, DMR ;
Powers, A ;
Fauci, AS .
JOURNAL OF INFECTIOUS DISEASES, 2003, 188 (03) :388-396
[2]   Short-cycle structured intermittent treatment of chronic HIV infection with highly active antiretroviral therapy: Effects on virologic, immunologic, and toxicity parameters [J].
Dybul, M ;
Chun, TW ;
Yoder, C ;
Hidalgo, B ;
Belson, M ;
Hertogs, K ;
Larder, B ;
Dewar, RL ;
Fox, CH ;
Hallahan, CW ;
Justement, JS ;
Migueles, SA ;
Metcalf, JA ;
Davey, RT ;
Daucher, M ;
Pandya, P ;
Baseler, M ;
Ward, DJ ;
Fauci, AS .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (26) :15161-15166
[3]   Combination antiretroviral therapy and the risk of myocardial infarction [J].
Friis-Moller, N ;
Sabin, CA ;
Weber, R ;
Monforte, AD ;
El-Sadr, WM ;
Reiss, P ;
Thiébaut, R ;
Morfeldt, L ;
De Wit, S ;
Pradier, C ;
Calvo, G ;
Law, MG ;
Kirk, O ;
Phillips, AN ;
Lundgren, JD ;
Lundgren, JD ;
Weber, R ;
Monteforte, AD ;
Bartsch, G ;
Reiss, P ;
Dabis, F ;
Morfeldt, L ;
De Wit, S ;
Pradier, C ;
Calvo, G ;
Law, MG ;
Kirk, O ;
Phillips, AN ;
Houyez, F ;
Loeliger, E ;
Tressler, R ;
Weller, I ;
Friis-Moller, N ;
Sabin, CA ;
Sjol, A ;
Lundgren, JD ;
Sawitz, A ;
Rickenbach, M ;
Pezzotti, P ;
Krum, E ;
Meester, R ;
Lavignolle, V ;
Sundström, A ;
Poll, B ;
Fontas, E ;
Torres, F ;
Petoumenos, K ;
Kjær, J ;
Hammer, S ;
Neaton, J .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (21) :1993-2003
[4]   Do protease inhibitors increase the risk for coronary heart disease in patients with HIV-1 infection? [J].
Klein, D ;
Hurley, LB ;
Quesenberry, CP ;
Sidney, S .
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2002, 30 (05) :471-477
[5]   Structured treatment interruption in patients with multidrug-resistant human immunodeficiency virus [J].
Lawrence, J ;
Mayers, DL ;
Hullsiek, KH ;
Collins, G ;
Abrams, DI ;
Reisler, RB ;
Crane, LR ;
Schmetter, BS ;
Dionne, TJ ;
Saldanha, JM ;
Jones, MC ;
Baxter, JD .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (09) :837-846
[6]   Predictors of trend in CD4-positive T-cell count and mortality among HIV-1-infected individuals with virological failure to all three antiretroviral-drug classes [J].
Ledergerber, B ;
Lundgren, JD ;
Walker, AS ;
Sabin, C ;
Justice, A ;
Reiss, P ;
Mussini, C ;
Wit, F ;
Monforte, AD ;
Weber, R ;
Fusco, G ;
Staszewski, S ;
Law, M ;
Hogg, R ;
Lampe, F ;
Gill, MJ ;
Castelli, F ;
Phillips, AN ;
Castelli, F ;
Fusco, GP ;
Gill, MJ ;
Hogg, R ;
Lampe, F ;
Law, M ;
Ledergerber, B ;
Lundgren, JD ;
Monforte, AD ;
Mussini, C ;
Phillips, AN ;
Reiss, P ;
Staszewski, S ;
Walker, AS ;
Rooney, P ;
Taylor, S ;
Couldwell, D ;
Austin, D ;
Block, M ;
Clemons, J ;
Finlayson, R ;
Law, M ;
Petoumenos, K ;
Quan, D ;
Smith, D ;
O'Connor, C ;
Gorton, C ;
Allen, D ;
Mulhall, B ;
Mutimer, K ;
Smith, D ;
Keeffe, N .
LANCET, 2004, 364 (9428) :51-62
[7]   Effect of prolonged discontinuation of successful antiretroviral therapy on CD4 T cells: a controlled, prospective trial [J].
Maggiolo, F ;
Ripamonti, D ;
Gregis, G ;
Quinzan, G ;
Callegaro, A ;
Suter, F .
AIDS, 2004, 18 (03) :439-446
[8]   Selection of drug-resistant HIV-1 mutants in response to repeated structured treatment interruptions [J].
Martinez-Picado, J ;
Morales-Lopetegi, K ;
Wrin, T ;
Prado, JG ;
Frost, SDW ;
Petropoulos, CJ ;
Clotet, B ;
Ruiz, L .
AIDS, 2002, 16 (06) :895-899
[9]   Emergence of minor populations of human immunodeficiency virus type 1 carrying the M184V and L90M mutations in subjects undergoing structured treatment interruptions [J].
Metzner, KJ ;
Bonhoeffer, S ;
Fischer, M ;
Karanicolas, R ;
Allers, K ;
Joos, B ;
Weber, R ;
Hirschel, B ;
Kostrikis, LG ;
Günthard, HF .
JOURNAL OF INFECTIOUS DISEASES, 2003, 188 (10) :1433-1443
[10]   AIDS across Europe, 1994-98: the EuroSIDA study [J].
Mocroft, A ;
Katlama, C ;
Johnson, AM ;
Pradier, C ;
Antunes, F ;
Mulcahy, F ;
Chiesi, A ;
Phillips, AN ;
Kirk, O ;
Lundgren, JD .
LANCET, 2000, 356 (9226) :291-296