Immunopathology of allergic contact dermatitis

被引：22

作者：

Agner Machado Martins, Luis Eduardo ^{[1
]}

Silva dos Reis, Vitor Manoel ^{[1
]}

机构：

[1] Univ Sao Paulo, Coll Med, Sao Paulo, Brazil

来源：

ANAIS BRASILEIROS DE DERMATOLOGIA | 2011年 / 86卷 / 03期

关键词：

Allergy and immunology; Dermatitis; allergic contact; contact; Hypersensitivity; REGULATORY T-CELLS; EPIDERMAL LANGERHANS CELLS; INTERCELLULAR-ADHESION MOLECULE-1; LANGERIN(+) DENDRITIC CELLS; CUTANEOUS INFLAMMATORY RESPONSES; CHEMOKINE RECEPTOR EXPRESSION; DELAYED-TYPE HYPERSENSITIVITY; REGIONAL LYMPH-NODES; IMMUNE-RESPONSES; HUMAN KERATINOCYTES;

D O I：

10.1590/S0365-05962011000300001

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100227 [皮肤病学];

摘要：

Allergic contact dermatitis is the consequence of an immune reaction mediated by T cells against low molecular weight chemicals known as haptens. It is a common condition that occurs in all races and age groups and affects the quality of life of those who present it. The immunological mechanism of this disease has been reviewed in recent decades with significant advance in its understanding. The metabolism and pathway of the haptens as well as the activation and mechanism of action of the cells responsible for both the immune reaction and its completion are discussed in this article.

引用

页码：419 / 430

页数：12

共 164 条

[1]

AIBA S, 1990, J IMMUNOL, V145, P2791

[2]

Dendritic cells differently respond to haptens and irritants by their production of cytokines and expression of co-stimulatory molecules [J].

Aiba, S ;

Terunuma, A ;

Manome, H ;

Tagami, H .

EUROPEAN JOURNAL OF IMMUNOLOGY, 1997, 27 (11) :3031-3038

[3]

Albanesi C, 1998, J INVEST DERMATOL, V110, P138

[4]

Albanesi C, 1999, J IMMUNOL, V162, P494

[5]

Albanesi C, 2001, J LEUKOCYTE BIOL, V70, P617

[6]

Effects of allergic dermatosis on health-related quality of life. [J].

Anderson R.T. ;

Rajagopalan R. .

Current Allergy and Asthma Reports, 2001, 1 (4) :309-315

[7]

IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis [J].

Antonopoulos, Christos ;

Cumberbatch, Marie ;

Mee, John B. ;

Dearman, Rebecca J. ;

Wei, Xiao-Qing ;

Liew, Foo Y. ;

Kimber, Ian ;

Groves, Richard W. .

JOURNAL OF LEUKOCYTE BIOLOGY, 2008, 83 (02) :361-367

[8]

Extravascular T-cell recruitment requires initiation begun by Vα14+ NKT cells and B-1B cells [J].

Askenase, PW ;

Szczepanik, M ;

Itakura, A ;

Kiener, C ;

Campos, RA .

TRENDS IN IMMUNOLOGY, 2004, 25 (08) :441-449

[9]

Statistical evaluation of the persistence of acquired hypersensitivity by standardized patch tests [J].

Ayala, F ;

Balato, N ;

Lembo, G ;

Patruno, C ;

Fabbrocini, G ;

Nofroni, I ;

Magliocchetti, N ;

Schena, D ;

Rafanelli, A ;

Seidenari, S ;

Motolese, A ;

Angelini, G ;

Tosti, A ;

Saccabusi, S ;

Pigatto, P ;

Lisi, P .

CONTACT DERMATITIS, 1996, 34 (05) :354-358

[10]

High and low doses of haptens dictate whether dermal or epidermal antigen-presenting cells promote contact hypersensitivity [J].

Bacci, S ;

Alard, P ;

Dai, RP ;

Nakamura, T ;

Streilein, JW .

EUROPEAN JOURNAL OF IMMUNOLOGY, 1997, 27 (02) :442-448

← 1 2 3 4 5 6 7 8 9 10 →