Difference in gene expression profiles between human CD4+CD25+ and CD4+CD25- T cells

被引:5
作者
Pati, N [1 ]
Ghosh, S [1 ]
Hessner, MJ [1 ]
Khoo, HJ [1 ]
Wang, XJ [1 ]
机构
[1] Childrens Hosp Wisconsin, Coll Med, Dept Pediat, Max McGee Natl Res Ctr Juvenile Diabet, Milwaukee, WI 53226 USA
来源
IMMUNOLOGY OF DIABETES II: PATHOGENESIS FROM MOUSE TO MAN | 2003年 / 1005卷
关键词
T cells; CD4+CD25+T cells; CD4+CD25; gene expression; microarray;
D O I
10.1196/annals.1288.043
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We studied the gene expression profiles of human CD4+CD25+ and CD4+CD25- T cells by using cDNA microarrays. Our preliminary results indicate that there are likely significant differences in the regulation of apoptosis, cell cycle, cytokine receptor, cell-cell interaction, and stress pathway genes between these two subtypes of T cells.
引用
收藏
页码:279 / 283
页数:5
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