Difference in gene expression profiles between human CD4+CD25+ and CD4+CD25- T cells
被引:5
作者:
Pati, N
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机构:
Childrens Hosp Wisconsin, Coll Med, Dept Pediat, Max McGee Natl Res Ctr Juvenile Diabet, Milwaukee, WI 53226 USAChildrens Hosp Wisconsin, Coll Med, Dept Pediat, Max McGee Natl Res Ctr Juvenile Diabet, Milwaukee, WI 53226 USA
Pati, N
[1
]
Ghosh, S
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Childrens Hosp Wisconsin, Coll Med, Dept Pediat, Max McGee Natl Res Ctr Juvenile Diabet, Milwaukee, WI 53226 USAChildrens Hosp Wisconsin, Coll Med, Dept Pediat, Max McGee Natl Res Ctr Juvenile Diabet, Milwaukee, WI 53226 USA
Ghosh, S
[1
]
Hessner, MJ
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机构:
Childrens Hosp Wisconsin, Coll Med, Dept Pediat, Max McGee Natl Res Ctr Juvenile Diabet, Milwaukee, WI 53226 USAChildrens Hosp Wisconsin, Coll Med, Dept Pediat, Max McGee Natl Res Ctr Juvenile Diabet, Milwaukee, WI 53226 USA
Hessner, MJ
[1
]
Khoo, HJ
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Childrens Hosp Wisconsin, Coll Med, Dept Pediat, Max McGee Natl Res Ctr Juvenile Diabet, Milwaukee, WI 53226 USAChildrens Hosp Wisconsin, Coll Med, Dept Pediat, Max McGee Natl Res Ctr Juvenile Diabet, Milwaukee, WI 53226 USA
Khoo, HJ
[1
]
Wang, XJ
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机构:
Childrens Hosp Wisconsin, Coll Med, Dept Pediat, Max McGee Natl Res Ctr Juvenile Diabet, Milwaukee, WI 53226 USAChildrens Hosp Wisconsin, Coll Med, Dept Pediat, Max McGee Natl Res Ctr Juvenile Diabet, Milwaukee, WI 53226 USA
Wang, XJ
[1
]
机构:
[1] Childrens Hosp Wisconsin, Coll Med, Dept Pediat, Max McGee Natl Res Ctr Juvenile Diabet, Milwaukee, WI 53226 USA
来源:
IMMUNOLOGY OF DIABETES II: PATHOGENESIS FROM MOUSE TO MAN
|
2003年
/
1005卷
关键词:
T cells;
CD4+CD25+T cells;
CD4+CD25;
gene expression;
microarray;
D O I:
10.1196/annals.1288.043
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
We studied the gene expression profiles of human CD4+CD25+ and CD4+CD25- T cells by using cDNA microarrays. Our preliminary results indicate that there are likely significant differences in the regulation of apoptosis, cell cycle, cytokine receptor, cell-cell interaction, and stress pathway genes between these two subtypes of T cells.