Reproductive disorders among male and female greenhouse workers

被引:47
作者
Bretveld, Reini W. [1 ]
Hooiveld, Mariette [1 ]
Zielhuis, Gerhard A. [1 ]
Pellegrino, Annelies [1 ]
van Rooij, Iris A. L. M. [1 ]
Roeleveld, Nel [1 ]
机构
[1] Radboud Univ Nijmegen, Nijmegen Med Ctr, Dept Epidemiol & Biostat, NL-6500 HB Nijmegen, Netherlands
关键词
pesticides; greenhouse workers; time-to-pregnancy; spontaneous abortion; reproductive disorders;
D O I
10.1016/j.reprotox.2007.08.005
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The aim of this study was to evaluate reproductive disorders in male and female greenhouse workers. In 2002, data were collected from 4872 Dutch greenhouse workers and 8133 referents through postal questionnaires with detailed questions on reproductive disorders of the most recent pregnancy, lifestyle habits, and occupational exposures (e.g. pesticides) prior to conception. Different reproductive outcome measures were compared between 957 male and 101 female greenhouse workers and 1408 referents by means of logistic regression analyses. The analyses of primigravidous couples showed a slightly elevated risk of prolonged TTP (ORwomen = 1.9; 95% CI: 0.8-4.4) and an increased risk of spontaneous abortion among female greenhouse workers (ORwomen = 4.0; 95% CI: 1.1-14.0). A decreased risk of preterm birth was found among male greenhouse workers (ORmen = 0.1; 95% CI: 0.03-0.5). This study may offer some evidence for the hypothesis that pesticide exposure affects human reproduction leading to spontaneous abortion and possibly to prolonged time-to-pregnancy. 0 2007 Elsevier Inc. All rights reserved.
引用
收藏
页码:107 / 114
页数:8
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