Formation of calcium-phosphate films with gradient composition on alumina ceramics by spray-pyrolysis technique and their biocompatibilities by cell-culture tests

被引：5

作者：

Aizawa, M

Yamamoto, T

Itatani, K

Suemasu, H

Nozue, A

Okada, I

机构：

[1] Sophia Univ, Fac Sci & Engn, Dept Chem, Chiyoda Ku, Tokyo 1028554, Japan

[2] Sophia Univ, Fac Sci & Engn, Dept Mech Engn, Chiyoda Ku, Tokyo 1028554, Japan

来源：

BIOCERAMICS | 2000年 / 192-1卷

关键词：

biocompatibility; cell culture; hydroxyapatite HA; porous coating; spray-pyrolysis technique; tricalcium phosphate;

D O I：

10.4028/www.scientific.net/KEM.192-195.103

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 [材料科学与工程]; 080502 [材料学];

摘要：

Calcium-phosphate films with gradient composition were formed on alumina ceramics by spray-pyrolysis technique. The crystalline phases of the resulting films were of the hydroxyapatite (HAp) and tricalcium phosphate (TCP). The TCP/HAp molar ratio increased on going from the substrate side to the surface. The resulting film was porous; the pore-size distributions mainly were in the ranges from 1000 to 10 mum, from 10 to 1 mum and submicrometers. A cell-culture test using an osteoblastic cell (MC3T3-E1) showed that the resulting porous films had excellent biocompatibilities.

引用

页码：103 / 106

页数：4