Association between Kaposi's sarcoma and atherosclerosis: implications for gammaherpesviruses and vascular disease

被引：16

作者：

Grahame-Clarke, C

Alber, DG

Lucas, SB

Miller, R

Vallance, P

机构：

[1] UCL, Royal Free & Univ Coll Med Sch, Dept Med, Ctr Clin Pharmacol, London WC1E 6JJ, England

[2] UCL, Wolfson Inst Biomed Sci, London WC1E 6BT, England

[3] St Thomas Hosp, United Med & Dent Sch, Dept Histopathol, London SE1 7EH, England

[4] Royal Free & Univ Coll Med Sch, Windeyer Inst Med Sci, Dept Sexually Transmitted Dis, London WC1E 6AU, England

来源：

AIDS | 2001年 / 15卷 / 14期

关键词：

D O I：

10.1097/00002030-200109280-00029

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The treatment of HIV-positive patients with protease inhibitors has been suggested to increase their risk of atherosclerosis. The cause of this accelerated atherogenesis is unknown, but on the basis of previous studies we postulated that it could be linked to the presence of human herpes-virus-8. A retrospective analysis of post-mortem reports showed a strong correlation between Kaposi's sarcoma and the presence of atheroma. This hypothesis merits further investigation.

引用

页码：1902 / 1904

页数：3

共 9 条

[1] Herpesvirus infection accelerates atherosclerosis in the apolipoprotein E-deficient mouse [J].