The two faces of transforming growth factor β in carcinogenesis

被引:619
作者
Roberts, AB [1 ]
Wakefield, LM [1 ]
机构
[1] NCI, Lab Cell Regulat & Carcinogenesis, Ctr Canc Res, Bethesda, MD 20892 USA
关键词
D O I
10.1073/pnas.1633291100
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:8621 / 8623
页数:3
相关论文
共 35 条
[1]   TGF-β signaling in cancer -: a double-edged sword [J].
Akhurst, RJ ;
Derynck, R .
TRENDS IN CELL BIOLOGY, 2001, 11 (11) :S44-S51
[2]   Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: a new model for metastasis [J].
Al-Mehdi, AB ;
Tozawa, K ;
Fisher, AB ;
Shientag, L ;
Lee, A ;
Muschel, RJ .
NATURE MEDICINE, 2000, 6 (01) :100-102
[3]   Dissemination and growth of cancer cells in metastatic sites [J].
Chambers, AF ;
Groom, AC ;
MacDonald, IC .
NATURE REVIEWS CANCER, 2002, 2 (08) :563-572
[4]   Defective repression of c-myc in breast cancer cells:: A loss at the core of the transforming growth factor β growth arrest program [J].
Chen, CR ;
Kang, YB ;
Massagué, J .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (03) :992-999
[5]  
DALAL BI, 1993, AM J PATHOL, V143, P381
[6]   Role of transforming growth factor-β signaling in cancer [J].
de Caestecker, MP ;
Piek, E ;
Roberts, AB .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2000, 92 (17) :1388-1402
[7]  
Engle SJ, 1999, CANCER RES, V59, P3379
[8]  
Glick AB, 1996, CANCER RES, V56, P3645
[9]   Transforming growth factor-β and breast cancer risk in women with mammary epithelial hyperplasia [J].
Gobbi, H ;
Dupont, WD ;
Simpson, JF ;
Plummer, WD ;
Schuyler, PA ;
Olson, SJ ;
Arteaga, CL ;
Page, DL .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1999, 91 (24) :2096-2101
[10]  
Gobbi H, 2000, HISTOPATHOLOGY, V36, P168