Evaluation of materials used for bedding encasement: Effect of pore size in blocking cat and dust mite allergen

被引:57
作者
Vaughan, JW [1 ]
McLaughlin, TE [1 ]
Perzanowski, MS [1 ]
Platts-Mills, TAE [1 ]
机构
[1] Univ Virginia, Asthma & Allerg Dis Ctr, Hlth Sci Ctr, Charlottesville, VA 22908 USA
关键词
mite avoidance; encasements; breathable fabrics; allergen avoidance;
D O I
10.1016/S0091-6749(99)70495-1
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Background: Mattress and pillow encasings are recommended for patients allergic to dust mites. Many encasements block allergen and are vapor permeable but do not allow free passage of air through the material, Recently, breathable fabrics made from tightly woven synthetic fibers or nonwoven synthetics have been recommend as encasements. Objective: The purpose of this study was to develop a method for testing encasement materials made of breathable fabrics. Methods: Dust samples containing a known quantity of allergen (Der f 1, Der p 1, and Fel d 1) were pulled across a variety of fabrics using a modified dust trap. Airflow through the dust trap was controlled with a vacuum pump. Five minutes after dust was introduced, the pump was shut off. A filter located downstream of the fabric collected allergen passing through the fabric during the test and was assayed with ELISA for the relevant allergen, Fabrics to be tested were obtained from manufacturers and specialty catalogs. Results: As the average pore size decreases, the airflow through a fabric becomes restricted, and the pressure differential created by the vacuum pump increases. Dust mite allergens (Der f 1 and Der p 1) were blocked below detectable limits by fabrics of less than 10 mu m in pore size. Fabrics with an average pore size of 6 mu m or less blocked cat allergen (Fel d 1). Conclusion: The method we developed provided a rigorous and reliable test for leakage of common indoor allergens through breathable barrier fabrics. Our results show that tightly woven fabrics and nonwoven synthetic fabrics can block common indoor allergens but still allow airflow.
引用
收藏
页码:227 / 231
页数:5
相关论文
共 9 条
[1]   REDUCING DOMESTIC EXPOSURE TO DUST MITE ALLERGEN REDUCES BRONCHIAL HYPERREACTIVITY IN SENSITIVE CHILDREN WITH ASTHMA [J].
EHNERT, B ;
LAUSCHADENDORF, S ;
WEBER, A ;
BUETTNER, P ;
SCHOU, C ;
WAHN, U .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1992, 90 (01) :135-138
[2]   A 2-SITE MONOCLONAL-ANTIBODY ELISA FOR THE QUANTIFICATION OF THE MAJOR DERMATOPHAGOIDES SPP ALLERGENS, DER P-I AND DER F-I [J].
LUCZYNSKA, CM ;
ARRUDA, LK ;
PLATTSMILLS, TAE ;
MILLER, JD ;
LOPEZ, M ;
CHAPMAN, MD .
JOURNAL OF IMMUNOLOGICAL METHODS, 1989, 118 (02) :227-235
[3]   AIRBORNE CONCENTRATIONS AND PARTICLE-SIZE DISTRIBUTION OF ALLERGEN DERIVED FROM DOMESTIC CATS (FELIS-DOMESTICUS) - MEASUREMENTS USING CASCADE IMPACTOR, LIQUID IMPINGER, AND A 2-SITE MONOCLONAL-ANTIBODY ASSAY FOR FEL-D-I [J].
LUCZYNSKA, CM ;
LI, Y ;
CHAPMAN, MD ;
PLATTSMILLS, TAE .
AMERICAN REVIEW OF RESPIRATORY DISEASE, 1990, 141 (02) :361-367
[4]  
*NAT HEART LUNG BL, 1997, 2 NIH NAT HEART LUNG
[5]   Preventive effect of bedding encasement with microfine fibers on mite sensitization [J].
Nishioka, K ;
Yasueda, H ;
Saito, H .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1998, 101 (01) :28-32
[6]   Double-blind controlled trial of effect of housedust-mite allergen avoidance on atopic dermatitis [J].
Tan, BB ;
Weald, D ;
Strickland, I ;
Friedmann, PS .
LANCET, 1996, 347 (8993) :15-18
[7]  
TOVEY ER, 1981, AM REV RESPIR DIS, V124, P630
[8]   MITE FECES ARE A MAJOR SOURCE OF HOUSE DUST ALLERGENS [J].
TOVEY, ER ;
CHAPMAN, MD ;
PLATTSMILLS, TAE .
NATURE, 1981, 289 (5798) :592-593
[9]  
1997, J ALLERGY CLIM IMMUN, V100, pS1