Rhodium-catalyzed [2+2+2] cyclotrimerization in an aqueous-organic biphasic system

被引：99

作者：

Kinoshita, H ^{[1
]}

Shinokubo, H ^{[1
]}

Ohsima, K ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Kyoto 6068501, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 26期

关键词：

D O I：

10.1021/ja035438o

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Macrocyclization via rhodium-catalyzed intramolecular [2 + 2 + 2] annulation of triynes has been explored in an aqueous-organic biphasic system. The biphasic system controls the concentration of hydrophobic substrates in the aqueous reaction phase and offers diluted reaction conditions without the use of a slow addition technique. The system also achieves selective cross-annulation between hydrophobic diynes and hydrophilic alkynes. Copyright © 2003 American Chemical Society.

引用

页码：7784 / 7785

页数：2

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