Chemotherapy of schistosomiasis: An update

被引：88

作者：

Cioli, D ^{[1
]}

机构：

[1] CNR, Ist Biol Cellulare, I-00137 Rome, Italy

来源：

PARASITOLOGY TODAY | 1998年 / 14卷 / 10期

关键词：

D O I：

10.1016/S0169-4758(98)01323-4

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

No major changes have occurred during the past 20 years regarding the therapeutic tools available to the clinician for the treatment of schistosomiasis. If anything, the two drugs (oxamniquine and metrifonate) that are valuable alternatives to the drug of choice (praziquantel) have become more difficult to procure in some African countries. Here, Donate Cioli summarizes some of the most recent and interesting laboratory studies on potential antischistosomal compounds, and then reviews recent developments related to the mechanism of action of praziquantel and to the possible emergence of praziquantel-resistant schistosomes.

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页码：418 / 422

页数：5

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共 50 条

[1] HUMAN SCHISTOSOMIASIS DUE TO SCHISTOSOMA-MEKONGI - DIAGNOSIS AND THERAPY [J].

AJANA, F ;

DEICAS, E ;

COLIN, JJ ;

POIRRIEZ, J ;

LEDUC, M ;

MOUTON, Y ;

CAILLAUX, M ;

FOURRIER, A ;

VERNES, A .

MEDECINE ET MALADIES INFECTIEUSES, 1986, 16 (03) :141-146

[2] ACTIVITY OF THE ARTEMETHER IN EXPERIMENTAL SCHISTOSOMIASIS-MANSONI [J].

ARAUJO, N ;

KOHN, A ;

KATZ, N .

MEMORIAS DO INSTITUTO OSWALDO CRUZ, 1991, 86 :185-188

[3] CYCLOPHILIN OF SCHISTOSOMA-JAPONICUM [J].

ARGAET, VP ;

MITCHELL, GF .

JOURNAL OF PARASITOLOGY, 1992, 78 (04) :660-664

[4] The development of resistance to anthelmintics: A perspective with an emphasis on the antischistosomal drug praziquantel [J].

Bennett, JL ;

Day, T ;

Liang, FT ;

Ismail, M ;

Farghaly, A .

EXPERIMENTAL PARASITOLOGY, 1997, 87 (03) :260-267

[5] PROTECTION AGAINST SCHISTOSOMIASIS PRODUCED BY CYCLOSPORIN-A [J].

BOUT, DT ;

DESLEE, D ;

CAPRON, AR .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1984, 33 (01) :185-186

[6]

BROWN P, 1994, NEW SCI, V144, P4

[7] Expression cloning and biochemical characterizations of recombinant cyclophilin proteins from Schistosoma mansoni [J].

Bugli, F ;

Khattab, A ;

Vigneti, E ;

Butler, R ;

Cioli, D ;

Klinkert, MQ .

PROTEIN EXPRESSION AND PURIFICATION, 1998, 12 (03) :340-346

[8]

CHAPPELL LH, 1988, TRANSPLANT P, V20, P291

[9] FAILURE OF THE TREATMENT BY PRAZIQUANTEL OF SCHISTOSOMIASIS - INTEREST OF RECTAL BIOPSY AND OF LONG FOLLOW-UP [J].

CHIDIAC, C ;

BEAUCAIRE, G ;

MOUTON, Y ;

CAILLAUX, M ;

FOURRIER, A .

MEDECINE ET MALADIES INFECTIEUSES, 1986, 16 (5BIS) :380-384

[10] ANTISCHISTOSOMAL DRUGS - PAST, PRESENT ... AND FUTURE [J].

CIOLI, D ;

PICAMATTOCCIA, L ;

ARCHER, S .

PHARMACOLOGY & THERAPEUTICS, 1995, 68 (01) :35-85

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