Going against the grain:: Chemotaxis and infection in Vibrio cholerae

被引:144
作者
Butler, SM [1 ]
Camilli, A [1 ]
机构
[1] Tufts Univ, Sch Med, Dept Mol Biol & Microbiol, Boston, MA 02111 USA
关键词
D O I
10.1038/nrmicro1207
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Chemotaxis is the process by which motile cells move in a biased manner both towards favourable and away from unfavourable environments. The requirement of this process for infection has been examined in several bacterial pathogens, including Vibrio cholerae. The single polar flagellum of Vibrio species is powered by a sodium-motive force across the inner membrane, and can rotate to produce speeds of up to 60 cell-body lengths (similar to 60 mu m) per second. Investigating the role of the chemotactic control of rapid flagellar motility during V. cholerae infection has revealed some unexpected and intriguing results.
引用
收藏
页码:611 / 620
页数:10
相关论文
共 126 条
[1]   THE BVGAS LOCUS NEGATIVELY CONTROLS MOTILITY AND SYNTHESIS OF FLAGELLA IN BORDETELLA-BRONCHISEPTICA [J].
AKERLEY, BJ ;
MONACK, DM ;
FALKOW, S ;
MILLER, JF .
JOURNAL OF BACTERIOLOGY, 1992, 174 (03) :980-990
[2]   Activation of methylesterase CheB: Evidence of a dual role for the regulatory domain [J].
Anand, GS ;
Goudreau, PN ;
Stock, AM .
BIOCHEMISTRY, 1998, 37 (40) :14038-14047
[3]   Two predicted chemoreceptors of Helicobacter pylori promote stomach infection [J].
Andermann, TM ;
Chen, YT ;
Ottemann, KM .
INFECTION AND IMMUNITY, 2002, 70 (10) :5877-5881
[4]  
[Anonymous], 1994, Vibrio cholerae and Cholera: Molecular to Global Perspectives
[5]  
BERG HC, 1972, NATURE, V239, P500, DOI 10.1038/239500a0
[6]   ToxR regulon of Vibrio cholerae and its expression in vibrios shed by cholera patients [J].
Bina, J ;
Zhu, J ;
Dziejman, M ;
Faruque, S ;
Calderwood, S ;
Mekalanos, J .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (05) :2801-2806
[7]   Ecology of Helicobacter pylori in the human stomach [J].
Blaser, MJ .
JOURNAL OF CLINICAL INVESTIGATION, 1997, 100 (04) :759-762
[8]   Chemotaxis in Vibrio cholerae [J].
Boin, MA ;
Austin, MJ ;
Häse, CC .
FEMS MICROBIOLOGY LETTERS, 2004, 239 (01) :1-8
[9]   Bright lights, abundant operons - Fluorescence and genomic technologies advance studies of bacterial locomotion and signal transduction: Review of the BLAST Meeting, Cuernavaca, Mexico, 14 to 19 January 2001 [J].
Bourret, RB ;
Charon, NW ;
Stock, AM ;
West, AH .
JOURNAL OF BACTERIOLOGY, 2002, 184 (01) :1-17
[10]   Molecular information processing: Lessons from bacterial chemotaxis [J].
Bourret, RB ;
Stock, AM .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (12) :9625-9628