Heparin-Induced Thrombocytopenia

被引:408
作者
Greinacher, Andreas [1 ]
机构
[1] Univ Med Greifswald, Inst Immunol & Transfusionsmed, Greifswald, Germany
关键词
MOLECULAR-WEIGHT HEPARIN; CONFORMATIONAL-CHANGES; PLATELET COUNT; IN-VITRO; ANTIBODIES; PLATELET-FACTOR-4; RISK; ACTIVATION; FONDAPARINUX; SCORE;
D O I
10.1056/NEJMcp1411910
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 64-year-old woman who is hospitalized with endocarditis and whose condition is clinically stable while she is receiving intravenous antibiotic agents has had a decrease in platelet count from 161,000 per cubic millimeter on day 7 of hospitalization to 60,000 per cubic millimeter on day 9. She has been receiving low-molecular-weight heparin at a dose of 40 mg per day since admission. How should her case be further evaluated and treated?
引用
收藏
页码:252 / 261
页数:10
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