Bone substitutes: An update

被引：1486

作者：

Giannoudis, PV ^{[1
]}

Dinopoulos, H ^{[1
]}

Tsiridis, E ^{[1
]}

机构：

[1] St James Univ Hosp, Acad Dept Orthopaed & Trauma, Leeds, W Yorkshire, England

来源：

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED | 2005年 / 36卷

关键词：

bone defects; allograft; autograft; bone graft substitute; scaffolds;

D O I：

10.1016/j.injury.2005.07.029

中图分类号：

R4 [临床医学];

学科分类号：

1002 [临床医学]; 100602 [中西医结合临床];

摘要：

Autograft is considered ideal for grafting procedures, providing osteoinductive growth factors, osteogenic cells, and an osteoconductive scaffold. Limitations, however, exist regarding donor site morbidity and graft availability. Allograft on the other hand, posses the risk of disease transmission. Synthetic graft substitutes Lack osteoinductive or osteogenic properties. Composite grafts combine scaffolding properties with biological elements to stimulate cell proliferation and differentiation and eventually osteogenesis. We present here an overview of bone grafts and graft substitutes available for clinical applications. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：20 / 27

页数：8

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