Zinc, Src and NMDA receptors - a transmembrane connection

被引:8
作者
Ascher, P [1 ]
机构
[1] Ecole Normale Super, Neurobiol Lab, F-75005 Paris, France
关键词
D O I
10.1038/619
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Zinc and tyrosine kinases produce opposite effects on the NMDA receptor; new evidence suggests that Src-induced potentiation is due to the relief of zinc inhibition.
引用
收藏
页码:173 / 175
页数:3
相关论文
共 15 条
[1]   Imaging free zinc in synaptic terminals in live hippocampal slices [J].
Budde, T ;
Minta, A ;
White, JA ;
Kay, AR .
NEUROSCIENCE, 1997, 79 (02) :347-358
[2]   Differential sensitivity of recombinant N-methyl-D-aspartate receptor subtypes to zinc inhibition [J].
Chen, NS ;
Moshaver, A ;
Raymond, LA .
MOLECULAR PHARMACOLOGY, 1997, 51 (06) :1015-1023
[3]   Zinc and brain injury [J].
Choi, DW ;
Koh, JY .
ANNUAL REVIEW OF NEUROSCIENCE, 1998, 21 :347-375
[4]  
CHRISTINE CW, 1990, J NEUROSCI, V10, P108
[5]  
FREDERICKSON CJ, 1989, INT REV NEUROBIOL, V31, P145
[6]  
Kohr G, 1996, J PHYSIOL-LONDON, V492, P445
[7]   THE INHIBITION OF SINGLE N-METHYL-D-ASPARTATE-ACTIVATED CHANNELS BY ZINC IONS ON CULTURED RAT NEURONS [J].
LEGENDRE, P ;
WESTBROOK, GL .
JOURNAL OF PHYSIOLOGY-LONDON, 1990, 429 :429-449
[8]   Src activation in the induction of long-term potentiation in CA1 hippocampal neurons [J].
Lu, YM ;
Roder, JC ;
Davidow, J ;
Salter, MW .
SCIENCE, 1998, 279 (5355) :1363-1367
[9]  
Paoletti P, 1997, J NEUROSCI, V17, P5711
[10]  
TRAYNELIS SF, IN PRESS J NEUROSCI