Monitoring the safety of licensed medicines

被引：11

作者：

Breckenridge, A ^{[1
]}

Woods, K ^{[1
]}

Raine, J ^{[1
]}

机构：

[1] Med & Healthcare Prod Regulatory Agcy, London SW8 5NQ, England

来源：

NATURE REVIEWS DRUG DISCOVERY | 2005年 / 4卷 / 07期

关键词：

D O I：

10.1038/nrd1778

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The withdrawal of the selective cyclooxygenase 2 inhibitor rofecoxib owing to cardiovascular side effects ignited debate about the need for major changes to current mechanisms for post-marketing surveillance (PMS) of drug safety. Here, we discuss the current mechanisms, whether they are being used appropriately, and consider the need for changes to regulatory systems.

引用

页码：1 / 3

页数：3

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