Alkaloids and saponins from blue cohosh

被引：29

作者：

Ali, Zulfiqar ^{[1
]}

Khan, Ikhlas A. ^{[1
,2
]}

机构：

[1] Univ Mississippi, Sch Pharm, Natl Ctr Nat Prod Res, Mississippi State, MS 38677 USA

[2] Univ Mississippi, Sch Pharm, Dept Pharmacognosy, Mississippi State, MS 38677 USA

来源：

PHYTOCHEMISTRY | 2008年 / 69卷 / 04期

关键词：

blue cobosh; Caulophyllum thalictroides; Berberidaceae; caulophyllumine A; caulophyllumine B; cauloside H;

D O I：

10.1016/j.phytochem.2007.10.011

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Blue cohosh, Caulophyllum thalictroides (L.) Michx. (Berberidaceae), is used primarily to cure menstrual disturbances and to ease childbirth. Alkaloids and saponins are considered to be responsible for its pharmacological activity. A detailed phytochemical investigation of blue cohosh resulted in the isolation of 15 compounds belonging to the alkaloids and the triterpene saponins. The structures of two alkaloids, caulophyllumines A (1) and B (2) and a saponin, cauloside H (3) both previously unknown were determined by spectroscopic techniques, including by 1- and 2-D NMR as well as by chemical analysis. (C) 2007 Published by Elsevier Ltd.

引用

页码：1037 / 1042

页数：6

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