Idiopathic granulomatous lobular mastitis

被引:125
作者
Pereira, Frederick A. [1 ,2 ]
Mudgil, Adarsh V. [2 ]
Macias, Edgar S. [1 ]
Karsif, Karen [3 ]
机构
[1] Cornell Univ, New York Med Coll, New York, NY 10029 USA
[2] Cornell Univ, Mt Sinai Sch Med, New York, NY 10029 USA
[3] Cornell Univ, Weill Med Coll, New York, NY 10029 USA
关键词
GIANT-CELL ARTERITIS; NEEDLE-ASPIRATION-CYTOLOGY; INVASIVE BREAST-CARCINOMA; FAT NECROSIS; DIABETIC MASTOPATHY; ERYTHEMA-NODOSUM; HIDRADENITIS SUPPURATIVA; WEGENERS-GRANULOMATOSIS; SURGICAL-MANAGEMENT; DUCTAL CARCINOMA;
D O I
10.1111/j.1365-4632.2011.05168.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100227 [皮肤病学];
摘要
Idiopathic granulomatous lobular mastitis (IGLM) is a rare breast condition with prominent skin findings. It is typically seen in young parous women. Painful breast masses, draining sinuses, scarring, and breast atrophy are the main clinical manifestations. IGLM can resemble a variety of other inflammatory and neoplastic processes of the breast. It is thought to result from obstruction and rupture of breast lobules. Extravasated breast secretions then induce an inflammatory reaction. Corynebacteria have also been implicated in the pathogenesis. Treatment is surgical, but systemic corticosteroids, methotrexate, and antibiotics also play a role.
引用
收藏
页码:142 / 151
页数:10
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