Pharmacogenetic response to albuterol among asthmatics

被引:17
作者
Corvol, Harriet [1 ]
Burchard, Esteban Gonzalez [1 ,2 ,3 ]
机构
[1] Univ Calif San Francisco, UCSF Lung Biol Ctr, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Inst Human Genet, San Francisco, CA 94143 USA
[3] Univ Calif San Francisco, Dept Biopharmaceut Sci, San Francisco, CA 94143 USA
关键词
D O I
10.2217/14622416.9.5.505
中图分类号
R9 [药学];
学科分类号
1007 [药学];
摘要
Pharmacogenetics offers to individualize asthma treatment by identifying genetic variants associated with drug efficacy or adverse events. Several studies have focused on pharmacogenetic associations with albuterol, the most commonly prescribed medication for asthma worldwide. However, pharmacogenetic associations have varied within and between studies and across populations. Herein, we focus on pharmacogenetic associations between genetic variants in the beta(2)-adrenergic receptor gene and bronchodilator response to albuterol among subjects with asthma.
引用
收藏
页码:505 / 510
页数:6
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