Aqueous phosphoester bond cleavage of dimethyl phosphate by Cp2MoCl2:: First reported case of hydrolytic cleavage on an unactivated phosphate diester by an organometallic complex

被引：42

作者：

Kuo, LY ^{[1
]}

Barnes, LA ^{[1
]}

机构：

[1] Lewis & Clark Coll, Dept Chem, Portland, OR 97219 USA

来源：

INORGANIC CHEMISTRY | 1999年 / 38卷 / 04期

关键词：

D O I：

10.1021/ic970462m

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The organometallic compound bis(eta(5)-cyclopentadienyl) molybdenum(IV) dichloride (Cp2MoCl2, Cp = beta(5)-C5H5) promotes the phosphotester bond cleavage of dimethyl phosphate with rate accelerations of 10(4) at pH 4.0. NMR spectral evidence suggests this phosphoester bond cleavage proceeds through a hydrolytic pathway where the aquated Cp2MoCl2 binds to the phosphate diester and then carries out an intramolecular attack with either a Cp2Mo-bound water or hydroxide. This is the first reported case of an organometallic complex that hydrolyzes an unactivated phosphate diester.

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页码：814 / 817

页数：4

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