Nuclear magnetic resonance studies of chromium(III) pyridinecarboxylate complexes

被引：38

作者：

Kingry, KF ^{[1
]}

Royer, AC ^{[1
]}

Vincent, JB ^{[1
]}

机构：

[1] Univ Alabama, Dept Chem, Tuscaloosa, AL 35487 USA

来源：

JOURNAL OF INORGANIC BIOCHEMISTRY | 1998年 / 72卷 / 1-2期

基金：

美国国家科学基金会;

关键词：

chromium; picolinic acid; nicotinic acid; nuclear magnetic resonance; chromium tris(picolinate);

D O I：

10.1016/S0162-0134(98)10067-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The H-1 and H-2 NMR spectra of a number of chromium(III) pyridinecarboxylates have been obtained. In contrast to previous reports (C. L. Broadhurst et al., J. Inorg. Biochem 66, (1997) 119), paramagnetically broadened and shifted resonances were observed as expected for ligands bound to the d(3) metal center. Using the combination of both H-1 and H-2 NMR and compounds with selective replacement of hydrogen with deuterium, all the hydrogen or deuterium resonances for some compounds could be located and assigned. The results indicate that paramagnetic NMR can be a valuable tool in characterizing Cr(III) pyridinecarboxylate complexes and that chromium(III) trispicolinate has complex behavior in solution. (C) 1998 Elsevier Science Inc. All rights reserved.

引用

页码：79 / 88

页数：10

共 47 条

[1] Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes [J].