Vγ2Vδ2+ T cells and anti-microbial immune responses

被引：55

作者：

Chen, ZW

Letvin, NL

机构：

[1] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, TB Res Unit, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Div Viral Pathogenesis, Boston, MA 02115 USA

来源：

MICROBES AND INFECTION | 2003年 / 5卷 / 06期

关键词：

gamma delta T cells; TCR; memory responses; immunity; infections; primates;

D O I：

10.1016/S1286-4579(03)00074-1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Vgamma2Vdelta2(+) T cells exist only in primates and constitute the majority of circulating human gammadelta T cells. Recent studies have demonstrated that this unique gammadelta T cell subpopulation can be a component of adaptive immune responses and contribute to anti-microbial immunity to infections. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

引用

页码：491 / 498

页数：8

共 72 条

[1] γδ T cell activation by chronic HIV infection may contribute to intrahepatic Vδ1 compartmentalization and hepatitis C virus disease progression independent of highly active antiretroviral therapy [J].