In vivo tracking of tumor-specific T cells

被引：53

作者：

Yee, C

Riddell, SR

Greenberg, PD

机构：

[1] Fred Hutchinson Canc Res Ctr, Seattle, WA 98109 USA

[2] Univ Washington, Med Ctr, Seattle, WA 98195 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2001年 / 13卷 / 02期

关键词：

D O I：

10.1016/S0952-7915(00)00196-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Novel immunologic assays now enable visualization of the antigen-specific response to an extent not previously possible. Assessment of not only the numeric frequency but also the functional properties of individual tumor-specific T cells in the endogenous and manipulated immune response has provided insights that will facilitate the development of immunotherapeutic strategies.

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收藏

页码：141 / 146

页数：6

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