Donor cell derived acute myeloid leukemia after allogeneic cord blood transplantation in a patient with adult T-cell lymphoma

被引：40

作者：

Matsunaga, T

Murase, K

Yoshida, M

Fujimi, A

Iyama, S

Kuribayashi, K

Sato, T

Kogawa, K

Hirayama, Y

Sakamaki, S

Kohda, K

Niitsu, Y

机构：

[1] Sapporo Med Univ, Dept Internal Med 4, Sch Med, Chuo Ku, Sapporo, Hokkaido, Japan

[2] Tokeidai Hosp, Dept Internal Med, Sapporo, Hokkaido, Japan

[3] Higashi Sapporo Hosp, Dept Internal Med, Sapporo, Hokkaido, Japan

[4] Asahikawa Red Cross Hosp, Dept Internal Med, Asahikawa, Hokkaido, Japan

来源：

AMERICAN JOURNAL OF HEMATOLOGY | 2005年 / 79卷 / 04期

关键词：

donor cell derived leukemia; cord blood transplantation; adult T-cell lymphoma;

D O I：

10.1002/ajh.20349

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a patient with adult T-cell lymphoma who developed acute myeloid leukemia (AML) after allogeneic cord blood transplantation (CBT). Fluorescence in situ hybridization (FISH) studies and molecular analysis using short tandem repeat (STR) sequences proved the AML to be of donor origin. Although 25 cases of donor cell leukemia (DCL) occurring after allogeneic bone marrow transplantation have previously been reported, there have been no reports of DCL after CBT. This case is the first-reported DCL patient after CBT.

引用

页码：294 / 298

页数：5

共 18 条

[1] B-cell lymphoma developing in the donor 9 years after donor-origin acute myeloid leukemia post bone marrow transplantation [J].