Effect of insulin on NO production by monocytes from patients with metabolic cardiovascular syndrome

被引：3

作者：

Suslova, TE ^{[1
]}

Sitozhevskii, AV

Ogurkova, ON

Gruzdeva, OV

Fedorova, TS

Karpov, RS

机构：

[1] Russian Acad Med Sci, Tomsk Res Ctr, Inst Cardiol, Siberian Div, Tomsk, Russia

[2] Siberian State Med Univ, Tomsk, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2005年 / 139卷 / 04期

关键词：

NO; insulin; monocytes; metabolic cardiovascular syndrome;

D O I：

10.1007/s10517-005-0302-6

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Basal and insulin-induced production of NO by monocytes significantly increased in patients with metabolic cardiovascular syndrome. Plasma insulin concentration in these patients was below the control. No intergroup differences were found in C-peptide concentration. A negative correlation was revealed between insulin-induced NO production by monocytes and C-peptide/insulin ratio in patients. The role of monocytes on the regulation of vascular tone via NO production in patients with metabolic cardiovascular syndrome is discussed.

引用

页码：391 / 393

页数：3

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