How to make a metalloprotein

被引：30

作者：

Bartnikas, TB ^{[1
]}

Gitlin, JD ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Edward Mallinkrodt Dept Pediat, St Louis, MO 63110 USA

来源：

NATURE STRUCTURAL BIOLOGY | 2001年 / 8卷 / 09期

关键词：

D O I：

10.1038/nsb0901-733

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Copper is an essential transition metal that plays a fundamental role in the biochemistry of all aerobic organisms. Recent work elucidating the structural mechanisms of copper delivery to superoxide dismutase provides insight into the cell biology of copper metabolism and serves as an example of how to understand the principles governing the incorporation of metals into proteins.

引用

页码：733 / 734

页数：2

共 15 条

[1] [Anonymous], 2001, METABOLIC MOL BASES
[2] [Anonymous], LANE MED LECT
[3] Casas M, 1998, COND MAT TH, V13, P273
[4] SUPEROXIDE RADICAL AND SUPEROXIDE DISMUTASES
FRIDOVICH, I
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1995, 64 : 97 - 112
[5] Heterodimeric structure of superoxide dismutase in complex with its metallochaperone
Lamb, AL
Torres, AS
O'Halloran, TV
Rosenzweig, AC
[J]. NATURE STRUCTURAL BIOLOGY, 2001, 8 (09) : 751 - 755
[6] Lamb AL, 1999, NAT STRUCT BIOL, V6, P724
[7] Crystal structure of the second domain of the human copper chaperone for superoxide dismutase
Lamb, AL
Wernimont, AK
Pufahl, RA
O'Halloran, TV
Rosenzweig, AC
[J]. BIOCHEMISTRY, 2000, 39 (07) : 1589 - 1595
[8] Heterodimer formation between superoxide dismutase and its copper chaperone
Lamb, AL
Torres, AS
O'Halloran, TV
Rosenzweig, AC
[J]. BIOCHEMISTRY, 2000, 39 (48) : 14720 - 14727
[9] Metallochaperones, an intracellular shuttle service for metal ions
O'Halloran, TV
Culotta, VC
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (33) : 25057 - 25060
[10] Femtomolar sensitivity of metalloregulatory proteins controlling zinc homeostasis
Outten, CE
O'Halloran, TV
[J]. SCIENCE, 2001, 292 (5526) : 2488 - 2492

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