Predicting the presence of plasma heparin using neural networks to analyze coagulation screening assay optical profiles

被引:14
作者
Givens, TB
Braun, P
Fischer, TJ
机构
[1] Organon Teknika Corporation, Durham, NC 27712
关键词
artificial intelligence; clotting time; neural network; blood coagulation modeling; heparin;
D O I
10.1016/S0010-4825(96)00023-6
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
A method for predicting the presence of heparin from coagulation screening assays is described and data are presented. This method incorporates the use of a multilayer perceptron trained through an error back-propagation algorithm in analyzing clotting optical data profiles. This method may lead to the identification of abnormalities from screening assays that might otherwise go undetected, or require additional testing to isolate. Copyright (C) 1996 Elsevier Science Ltd.
引用
收藏
页码:463 / 476
页数:14
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