alpha-hydroxyalkyl(benzyl)furazans and alpha-hydroxyalkyl(benzyl)furoxans - Synthesis and reactivity

被引：13

作者：

Blinnikov, AN ^{[1
]}

Kulikov, AS ^{[1
]}

Makhova, NN ^{[1
]}

Khmelnitskii, LI ^{[1
]}

机构：

[1] RUSSIAN ACAD SCI,ND ZELINSKII ORGAN CHEM INST,MOSCOW 117913,RUSSIA

来源：

RUSSIAN CHEMICAL BULLETIN | 1996年 / 45卷 / 07期

关键词：

furazans; furoxans; reduction; nucleophilic substitution;

D O I：

10.1007/BF01431809

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A general,and simple preparative method for the synthesis of alpha-hydroxyalkyl(benzyI)furazan and -furoxan derivatives is proposed. The method involves reduction of acyl or ethoxycarbonyl substituents in these heterocyclic compounds with NaBH4 in ethanol. Based on the alcohols thus prepared, a number of previously unknown functional derivatives (alpha-nitroxyalkyl-,alpha-haloalkyl-, and alpha-azidoalkylfurazans and -furoxans) have been synthesized.

引用

页码：1692 / 1698

页数：7

共 12 条

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