Is the spinal motion segment a diarthrodial polyaxial joint: What a nice nucleus like you doing in a joint like this?

被引:50
作者
Shapiro, Irving M. [1 ]
Vresilovic, Edward J. [2 ]
Risbud, Makarand V. [1 ]
机构
[1] Thomas Jefferson Univ, Jefferson Med Coll, Dept Orthopaed Surg, Div Orthopaed Res, Philadelphia, PA 19107 USA
[2] Penn State Univ, Milton S Hershey Med Ctr, Dept Orthopaed Surg, Hershey, PA 17033 USA
基金
美国国家卫生研究院;
关键词
Diarthrodial joint; Nucleus pulposus; Annulus fibrosus; Intervertebral disk; Arthrotome; Synovial cells; Lubricin; Ext1; Notochord; Hyaluronan; Aggrecan; Joint biomechanics; HUMAN INTERVERTEBRAL DISC; ARTICULAR-CARTILAGE FORMATION; SYNOVIAL JOINT; IN-VITRO; CELLS; LUBRICIN; DEGENERATION; NOTOCHORD; SKELETOGENESIS; MECHANOBIOLOGY;
D O I
10.1016/j.bone.2011.12.004
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
This review challenges an earlier view that the intervertebral joint could not be classified as a diarthrodial joint and should remain as an amphiarthrosis. However, a careful analysis of the relevant literature and in light of more recent studies, it is clear that while some differences exist between the spinal articulation and the generic synovial joint, there are clear structural, functional and developmental similarities between the joints that in sum outweigh the differences. Further, since the intervertebral motion segment displays movement in three dimensions and the whole spine itself provides integrated rotatory movements, it is proposed that it should be classified not as an amphiarthrose, "a slightly moveable joint" but as a complex polyaxial joint. Hopefully, reclassification will encourage further analysis of the structure and function of the two types of overlapping joints and provide common new insights into diseases that afflict the many joints of the human skeleton. (C) 2011 Elsevier Inc. All rights reserved.
引用
收藏
页码:771 / 776
页数:6
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