Catalytic asymmetric carbon-carbon bond forming reactions: preparation of optically enriched 2-aryl propionic acids by a catalytic asymmetric hydroboration-homologation sequence

被引：36

作者：

Chen, AC ^{[1
]}

Ren, L ^{[1
]}

Crudden, CM ^{[1
]}

机构：

[1] Univ New Brunswick, Dept Chem, Fredericton, NB E3B 6E2, Canada

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 07期

关键词：

D O I：

10.1039/a809435g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new catalytic asymmetric one-carbon homologation strategy has been developed which employs a rhodium catalyzed asymmetric hydroboration followed by homologation with LiCHCl2 and oxidation to generate 2-arylpropionic acids of high enantiomeric purity.

引用

页码：611 / 612

页数：2

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