Low-power diode laser stimulation of surgical osteochondral defects: Results after 24 weeks

被引:25
作者
Guzzardella, GA [1 ]
Tigani, D [1 ]
Torricelli, P [1 ]
Fini, M [1 ]
Martini, L [1 ]
Morrone, G [1 ]
Giardino, R [1 ]
机构
[1] Rizzoli Orthoped Inst, Dept Expt Surg, Div 7, I-40136 Bologna, Italy
来源
ARTIFICIAL CELLS BLOOD SUBSTITUTES AND IMMOBILIZATION BIOTECHNOLOGY | 2001年 / 29卷 / 03期
关键词
D O I
10.1081/BIO-100103047
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 [微生物学]; 0836 [生物工程]; 090102 [作物遗传育种]; 100705 [微生物与生化药学];
摘要
The purpose of this study was to evaluate osteochondral lesions of the knee, treated intraoperatively with low-power laser stimulation, and assess results at 24 weeks. Surgery was performed under general anesthesia on six rabbits; a bilateral osteochondral lesion was created in the femoral medial condyles with a drill. All of the left lesions underwent immediate stimulation using the diode Ga-Al-As laser (780nm), whereas the right knees were left untreated as control group. After 24 weeks, the explants from the femoral condyles, either treated employing laser energy or left untreated, were examined histomorphometrically. Results obtained on the lased condyles showed good cell morphology and a regular aspect of the repaired osteocartilaginous tissue.
引用
收藏
页码:235 / 244
页数:10
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