Bioactive phenolic glycosides from Amburana cearensis

被引：60

作者：

Bravo, JA

Sauvain, M

Gimenez, A

Muñoz, V

Callapa, J

Le Men-Olivier, L

Massiot, G

Lavaud, C

机构：

[1] CPCBAI, CNRS, UPRESA 6013, Lab Pharmacognosie, F-51687 Reims 2, France

[2] Univ Mayor San Andres, ORSTOM, Inst Boliviano Biol Altura, Lab Farmacognosia, La Paz, Bolivia

[3] CPCBAI, Antenne ORSTOM, F-51687 Reims, France

[4] Univ Mayor San Andres, Inst Invest Farmaco Bioquim, La Paz, Bolivia

[5] Univ Mayor San Andres, Inst Invest Quim, La Paz, Bolivia

来源：

PHYTOCHEMISTRY | 1999年 / 50卷 / 01期

关键词：

Amburana cearensis; Leguminosae; stem-bark; phenolic glycosides; coumarin; biological activities;

D O I：

10.1016/S0031-9422(98)00497-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Coumarin (1) and two new phenolic glycosides have been isolated from the stem bark of Amburana cearensis, a tree reported in the Chacobo pharmacopoeia to be used against fever-causing diseases. The novel compounds were identified as: 4-(O-beta-D-glucopyranosyl)-hydroxy-7-(3',4'-dihydroxy-benzoyl)-benzyl alcohol (2) and 4-(O-beta-D-glucopyranosyl)-hydroxy-7-(3'-methoxy-,4'-hydroxy-benzoyl)-benzyl alcohol (3). All three compounds were assayed in vitro for antimalarial, antiprotozoal antifungal and antibacterial activities. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：71 / 74

页数：4

共 11 条

[1]

ADESINA S K, 1983, Fitoterapia, V54, P141

[2] PHENOLIC, IRIDOID AND IONYL GLYCOSIDES FROM HOMALIUM-CEYLANICUM [J].