RNA interference: a multifaceted innate antiviral defense

被引：10

作者：

Kumar, Ajit ^{[1
]}

机构：

[1] George Washington Univ, Sch Med, Dept Biochem & Mol Biol, Washington, DC 20037 USA

来源：

RETROVIROLOGY | 2008年 / 5卷 / 1期

关键词：

D O I：

10.1186/1742-4690-5-17

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The RNA interference mechanism utilizes short RNA duplexes to either suppress or induce target gene expression. Post-transcriptional regulation mediated by microRNA is an integral component of innate antiviral defense. The magnitude and the efficiency of viral restriction guided by RNA-based defenses, as well as the full physiological implication of host-pathogen engagement, constitute exciting areas of investigation in the biology of non-coding RNAs.

引用

页数：4

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