Brief recommendations on the management of adult patients with familial hypercholesterolemia during the COVID-19 pandemic

被引:52
作者
Banach, Maciej [1 ,2 ,3 ]
Penson, Peter E. [4 ]
Fras, Zlatko [5 ]
Vrablik, Michal [6 ,7 ]
Pella, Daniel [8 ,9 ]
Reiner, Zeljko [10 ]
Nabavi, Seyed Mohammad [11 ]
Sahebkar, Amirhossein [12 ,13 ,14 ]
Kayikcioglu, Meral [15 ]
Daccord, Magdalena [16 ]
机构
[1] Med Univ Lodz, Dept Hypertens, Chair Nephrol & Hypertens, Lodz, Poland
[2] Polish Mothers Mem Hosp Res Inst PMMHRI, Lodz, Poland
[3] Univ Zielona Gora, Cardiovasc Res Ctr, Zielona Gora, Poland
[4] Liverpool John Moores Univ, Sch Pharm & Biomol Sci, Liverpool, Merseyside, England
[5] Univ Ljubljana, Univ Med Ctr Ljubljana, Ctr Prevent Cardiol, Div Med,Med Fac, Ljubljana, Slovenia
[6] Charles Univ Prague, Fac Med 1, Dept Internal Med 3, Prague, Czech Republic
[7] Gen Fac Hosp Prague, Prague, Czech Republic
[8] Safarik Univ, East Slovak Inst Cardiovasc Dis, Dept Cardiol, Kosice, Slovakia
[9] Safarik Univ, Fac Med, Kosice, Slovakia
[10] Zagreb Univ, Univ Hosp Ctr Zagreb, Sch Med, Dept Internal Dis, Zagreb, Croatia
[11] Baqiyatallah Univ Med Sci, Baqiyatallah Hosp, Tehran, Iran
[12] Mashhad Univ Med Sci, Pharmaceut Technol Inst, Biotechnol Res Ctr, Mashhad, Razavi Khorasan, Iran
[13] Mashhad Univ Med Sci, Neurogen Inflammat Res Ctr, Mashhad, Razavi Khorasan, Iran
[14] Mashhad Univ Med Sci, Sch Pharm, Mashhad, Razavi Khorasan, Iran
[15] Ege Univ, Sch Med, Dept Cardiol, Izmir, Turkey
[16] FH Europe, Budapest, Hungary
关键词
Cholesterol; Coronavirus; Covid-19; Prevention; Risk stratification; Statins; Therapy; CARDIOVASCULAR RISK;
D O I
10.1016/j.phrs.2020.104891
中图分类号
R9 [药学];
学科分类号
100702 [药剂学];
摘要
Individuals with Familial Hypercholesterolaemia (FH) are at very high risk of cardiovascular disease, which is associated with poor outcomes from coronavirus infections. COVID-19 puts strain on healthcare systems and may impair access to routine FH services. On behalf of the International Lipid Expert Panel (ILEP) and the European FH Patient Network (FH Europe), we present brief recommendations on the management of adult patients with FH during the COVID-19 pandemic. We discuss the implications of COVID-19 infections for FH patients, the importance of continuing lipid-lowering therapy where possible, issues relating to safety monitoring and service delivery. We summarise the evidence for additional benefits of statins and other lipid-lowering drugs during viral infections. The recommendations do not override in any way the individual responsibility of physicians to make appropriate and accurate decisions taking into account the condition of a given patient and the doses, rules, and regulations applicable to drugs and devices at the time of their prescription/use.
引用
收藏
页数:4
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