NalO4-mediated selective oxidative halogenation of alkenes and aromatics using alkali metal halides

被引：151

作者：

Dewkar, GK ^{[1
]}

Narina, SV ^{[1
]}

Sudalai, A ^{[1
]}

机构：

[1] Natl Chem Lab, Chem Engn & Proc Dev Div, Pune 411008, Maharashtra, India

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 23期

关键词：

D O I：

10.1021/ol0358206

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

NalO(4) oxidizes alkali metal halides efficiently in aqueous medium to halogenate alkenes and aromatics and produce the corresponding halo derivatives in excellent regio and stereoselectivity. The system also demonstrates the asymmetric version of bromo hydroxylation using beta-cyclodextrin complexes, resulting in moderate ee.

引用

页码：4501 / 4504

页数：4

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