Water-accelerated tandem Claisen rearrangement-catalytic asymmetric carboalumination

被引：40

作者：

Wipf, P ^{[1
]}

Ribe, S ^{[1
]}

机构：

[1] Univ Pittsburgh, Dept Chem, Pittsburgh, PA 15260 USA

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 10期

关键词：

D O I：

10.1021/ol015816z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The addition of stoichiometric quantities of water accelerates both the trimethylaluminum mediated aromatic Claisen reaction and the chiral zirconocene-catalyzed asymmetric carboalumination of terminal alkenes, The two reactions occur in a tandem sequence resulting in the selective formation of two new C-C and one C-O bond after oxidative quench of the intermediate trialkylalane.

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页码：1503 / 1505

页数：3

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