Serum cystatin C as an endogenous marker of renal function in patients with chronic kidney disease

被引：31

作者：

Hojs, Radovan ^{[2
]}

Bevc, Sebastjan ^{[1
]}

Ekart, Robert ^{[1
]}

Gorenjak, Maksimijan ^{[3
]}

Puklavec, Ludvik ^{[4
]}

机构：

[1] Univ Klin Ctr Maribor, Klin Interno Med, Oddelek Dializo, Maribor 2000, Slovenia

[2] Univ Med Ctr Maribor, Dept Nephrol, Clin Internal Med, Maribor, Slovenia

[3] Univ Med Ctr Maribor, Dept Clin Chem, Maribor, Slovenia

[4] Univ Med Ctr Maribor, Dept Nucl Med, Clin Internal Med, Maribor, Slovenia

来源：

RENAL FAILURE | 2008年 / 30卷 / 02期

关键词：

(51)CrEDTA clearance; chronic kidney disease; glomerular filtration rate; serum cystatin C; serum creatinine;

D O I：

10.1080/08860220701810315

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The estimation of the glomerular filtration rate (GFR) is an essential part of the evaluation of patients with chronic kidney disease (CKD). Recently, serum cystatin C has been proposed as a new endogenous marker of GFR. Authors compared scrum creatinine, creatinine clearance calculated from Cockcroft and Gault formula and serum cystatin C against (51)CrEDTA clearance in 252 patients with CKD and GFR <90 mL/min/1.73 m(2). Analysis of correlations and diagnostic accuracy (receiver operating characteristic curves) of different GFR markers indicate that serum cystatin C is a more reliable marker of GFR in patients with CKD than serum creatinine.

引用

页码：181 / 186

页数：6

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