Selective membrane sensors for free radical analysis based on potentiometric and CHEMFET devices

The present paper describes a completely new method for radical determination based on spin trapping reaction suitably adapted for the electrochemical determination of radical species. First of all benzylidenephenylnitrone was synthesized and then immobilised in a PVC-sebacate membrane. Lastly, this membrane was used to assemble different kinds of selective potentiometric sensors and CHEMFETs. These analytical devices were then used to determine free radical species, principally the anion superoxide radical and, in one case, also the hydroxide radical.