Indium mediated allylation in peptide and protein functionalization

被引：21

作者：

Alam, Jenefer ^{[1
]}

Keller, Thomas H. ^{[1
]}

Loh, Teck-Peng ^{[1
]}

机构：

[1] Nanyang Technol Univ, Sch Phys & Math Sci, Div Chem & Biol Chem, Singapore 637371, Singapore

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 32期

关键词：

UNNATURAL AMINO-ACIDS; N-TERMINAL SERINE; AQUEOUS-SOLUTION; CHEMISTRY; METATHESIS; COMPLEXES;

D O I：

10.1039/c1cc12926k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Indium-mediated allylation has been used in the site-selective functionalization of N-terminal aldehydes of peptides and proteins. This is the first demonstration of indium-mediated C-C bond formation in protein labelling studies under mild and environmentally friendly conditions.

引用

页码：9066 / 9068

页数：3

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