Advances in organic transistor-based biosensors: from organic electrochemical transistors to electrolyte-gated organic field-effect transistors

被引:228
作者
Kergoat, Loig [1 ,3 ]
Piro, Benoit [1 ]
Berggren, Magnus [3 ]
Horowitz, Gilles [1 ,2 ]
Minh-Chau Pham [1 ]
机构
[1] Univ Paris Diderot, Lab ITODYS, UMR CNRS 7086, F-75205 Paris 13, France
[2] Ecole Polytech, UMR CNRS 7647, LPICM, F-91128 Palaiseau, France
[3] Linkoping Univ, Dept Sci & Technol ITN, S-60174 Norrkoping, Sweden
关键词
Organic thin-film transistors; Electrolyte-gated transistors; Water-gated transistors; Biosensors; THIN-FILM TRANSISTORS; DNA HYBRIDIZATION; ENZYME SWITCH; POLYMER; PH; DEVICE; CONDUCTIVITY; INTEGRATION; FABRICATION; DIELECTRICS;
D O I
10.1007/s00216-011-5363-y
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Organic electronics have, over the past two decades, developed into an exciting area of research and technology to replace classic inorganic semiconductors. Organic photovoltaics, light-emitting diodes, and thin-film transistors are already well developed and are currently being commercialized for a variety of applications. More recently, organic transistors have found new applications in the field of biosensors. The progress made in this direction is the topic of this review. Various configurations are presented, with their detection principle, and illustrated by examples from the literature.
引用
收藏
页码:1813 / 1826
页数:14
相关论文
共 85 条
[1]   The measurement of alkaline phosphatase at nanomolar concentration within 70 s using a disposable microelectrochemical transistor [J].
Astier, Y ;
Bartlett, PN .
BIOELECTROCHEMISTRY, 2004, 64 (01) :53-59
[2]  
Badhwar S, 2008, J SENSORS
[3]   Organic thin-film transistors as transducers for (bio) analytical applications [J].
Bartic, C ;
Borghs, G .
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2006, 384 (02) :354-365
[4]   Field-effect detection of chemical species with hybrid organic/inorganic transistors [J].
Bartic, C ;
Campitelli, A ;
Borghs, S .
APPLIED PHYSICS LETTERS, 2003, 82 (03) :475-477
[5]   Monitoring pH with organic-based field-effect transistors [J].
Bartic, C ;
Palan, B ;
Campitelli, A ;
Borghs, G .
SENSORS AND ACTUATORS B-CHEMICAL, 2002, 83 (1-3) :115-122
[6]   Microelectrochemical enzyme transistors [J].
Bartlett, PN ;
Astier, Y .
CHEMICAL COMMUNICATIONS, 2000, (02) :105-112
[7]   ENZYME SWITCH RESPONSIVE TO GLUCOSE [J].
BARTLETT, PN ;
BIRKIN, PR .
ANALYTICAL CHEMISTRY, 1993, 65 (08) :1118-1119
[8]   Electroactivity, stability and application in an enzyme switch at pH 7 of poly(aniline)-poly(styrenesulfonate) composite films [J].
Bartlett, PN ;
Wang, JH .
JOURNAL OF THE CHEMICAL SOCIETY-FARADAY TRANSACTIONS, 1996, 92 (20) :4137-4143
[9]   A microelectrochemical switch responsive to NADH [J].
Bartlett, PN ;
Wang, JH ;
Wallace, ENK .
CHEMICAL COMMUNICATIONS, 1996, (03) :359-360
[10]   Measurement of low glucose concentrations using a microelectrochemical enzyme transistor [J].
Bartlett, PN ;
Wang, JH ;
James, W .
ANALYST, 1998, 123 (02) :387-392