Are quantitative functional measures more sensitive to worsening MS than traditional measures?

被引：31

作者：

Schwid, SR

Goodman, AD

Apatoff, BR

Coyle, PK

Jacobs, LD

Krupp, LB

Miller, AE

Wende, KE

Brownscheidle, CM

机构：

[1] Univ Rochester, Med Ctr, Dept Neurol, Rochester, NY 14627 USA

[2] Cornell Univ, Med Ctr, New York Hosp, Dept Neurol, New York, NY 10021 USA

[3] SUNY Stony Brook, Dept Neurol, Stony Brook, NY 11794 USA

[4] SUNY Buffalo, Dept Neurol, Buffalo, NY 14260 USA

[5] Maimonides Med Ctr, Dept Neurol, Brooklyn, NY 11219 USA

来源：

NEUROLOGY | 2000年 / 55卷 / 12期

关键词：

D O I：

10.1212/WNL.55.12.1901

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors used data collected prospectively during a multicenter trial in 133 patients with secondary progressive MS to assess the relative sensitivity of quantitative functional tests and traditional measures, including the Expanded Disability Status Scale (EDSS) and Ambulation Index. Quantitative functional measures worsened in 69% of patients during an average of 6 months of observation, whereas the Clinical Global Impression of Change worsened in 33% and the EDSS worsened in 25% of patients. These changes should be interpreted in the context of the test-retest reliability for each measure.

引用

页码：1901 / 1903

页数：3

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